Cannabidiol and cannabinol are just two of more than 100 cannabinoids that have been found in cannabis plants. The Endocannabinoid System is a group of chemicals that can interact with your body’s receptors.
You’re likely to be more familiar with CBD than CBN if you’re like many people.
Since legalization of recreational cannabis in some states, CBD products have seen a surge in popularity. Many people use CBD products for their anxiety symptoms and to manage chronic pain.
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CBN’s potential benefits have not been studied in humans. However, there are some small studies that show it can reduce pain and act like a sedative.
Let’s look at the benefits and differences between CBD and CBN.
What are some of the benefits and uses for CBD?
CBD is not psychoactive, so it won’t give you a high like Tetrahydrocannabinol. It is used to treat anxiety and pain, as well as other conditions.
Although research on CBD is still in its early stages, some preliminary studies have shown promising results.
CBD can be purchased in many forms including:
gummies
Oils and Tinctures
Creams and lotions
pills and capsules
Vapes
Here are the results of research so far on CBD’s potential health benefits.
Management of anxiety and depression
Early research has shown that CBD could be an alternative to traditional medication for treating anxiety or depression. Although researchers are still unsure how CBD works, it is believed that CBD’s beneficial effects could be due its action on 5HT1A receptors.
A 2019 Brazilian study showed that 57 participants received either a placebo, 150, 300, and 600 mg of CBD before they gave a speech. Researchers found that CBD 300 mg significantly decreased anxiety in participants.
Participants with anxiety and sleep disorders were treated with CBD daily in a 2019 study. A month later, 79% of participants reported an improvement in anxiety symptoms.
Neuroprotection and seizure reduction
A 2020 review by studies found that CBD could be an option to treat a number of neurodegenerative disorders.
CBDs potential for treating:
Parkinson’s Disease
Alzheimer’s Disease
epilepsy
Multiple Sclerosis
The Food and Drug Administration has approved CBD under the name Epidiolex to treat Lennox–Gastaut and Dravet Syndromes (two rare forms epilepsy) and seizures due to tuberous Sclerosis Complex (TSC).
Sleep
CBD is reported to help people sleep.
Although there is some evidence to suggest that CBD can improve sleep quality, more research is necessary to fully understand its potential.
The same 2019 study by Dr. Scott Shannon found that 66.7 per cent of participants experienced improved sleep quality after taking between 25 and 175 mg CBD daily.
Pain relief
Research found that CBD can be used to reduce chronic pain. It interacts with the body’s endocrine system.
A 2018 study found that seven patients who had just undergone a kidney transplant received 50 to 150mg of CBD daily for three weeks. Two patients experienced complete pain relief, while four others saw partial improvement. One patient had no change at all.
Treatment for cancer
Research found that Cannabis Oil can reduce the symptoms of cancer treatment such as nausea and pain.
Early studies also showed that CBD might have anticancer properties.
A 2019 Review of Studies Examining in vitro as well as in vivo studies, CBD was found to slow down tumor growth and increase cell death. The study focused on pancreatic carcinoma.
What are CBN’s benefits and uses?
CBN is formed from the THC, a psychoactive cannabinoid. Although it is mildly psychoactive, CBN doesn’t usually produce a high as THC.
CBD is more frequently studied than CBN. There is very little research on the potential benefits of CBN at this point. CBN products are often marketed as sleeping aids. However, more research is needed to support these claims.
These are some common uses of CBN and their potential benefits:
Sleep
Many people claim that CBN helps with sleep. There is only one study that shows CBN can be used as a sedative. It was done by 1975TrustedSource with five men.
Participants who were given THC and CBN combined had stronger sedative effects that those who received THC only.
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Pain relief
A 2019 Rat Study showed that CBD and CBN could reduce myofascial pain. Combining CBN with CBD is more effective than either one.
Researchers concluded that CBN or CBD could be used to treat pain caused by temporomandibular disorder and fibromyalgia.
Neuroprotective effects
A 2005 rat study showed that CBN could delay the onset of amyotrophic lateral sclerosis. It’s unclear if CBN has the same effect on humans.
Anti-inflammatory properties
Some evidence has been found in rats indicating that CBN may help reduce arthritis-related inflammation. Human research is necessary to fully comprehend its potential benefits.
What are the main differences between CBD, CBN and
- Use CBD CBN
- Depression & anxiety
- Sleep
- Seizures (FDA approved for 2 rare forms epilepsy and TSC).
- Pain relief
- Neuroprotection
- Anti-inflammation
- Despite having similar names, CBD is different from CBN.
The second most commonly CBD cannabinoid is found in cannabis plants. Cannabis plants can be bred to produce higher levels of CBD.
CBN can’t be adjusted by manufacturers as it is created from THC. THC can be broken down into CBN by heating it.
Both cannabinoids are still being researched in an early stage. CBD is still being researched. This is why CBD is often easier to find.
CBD has been FDA approved for two types of epilepsy and seizures due to TSC. CBN has not been approved by the FDA to treat any condition.
What side effects could CBD have on CBN vs CBD?
CBD is generally safe and has an excellent safety profile. These are the most common side effects of CBD:
diarrhea
tiredness
Changes in appetite and weight
Dose-dependent CBD may increase the risk for liver damage when combined with other medications such as:
- leflunomide
- Lomotapide
- mipomersen
- pexidartinib
- teriflunomide
- Valproate
CBN has no side effects, but this doesn’t necessarily mean that they aren’t there. This is because CBN has not been thoroughly studied enough to find them.
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Discuss CBD and CBN with your doctor.
Before you start taking CBD, CBN or any other supplements, it is important to consult a doctor. A doctor will recommend a starting dosage and inform you if there are any potential interactions with your medications.
While CBD and CBN might be able to help with your current treatment, they should not be used as a substitute for existing therapies.
Takeaway
CBN and CBD can be found in cannabis plants. Both are still being researched.
CBD has been the subject of more research. Some evidence suggests that CBD can be used to treat chronic pain, anxiety, depression, and other conditions.
CBN requires more human research before we can draw conclusions about its potential benefits.
