Ground-breaking news: oxygen optimization with Slab51 probiotic formulation.

Multi-Strain Probiotic Product (Sivomixx®800) Improves Oxygen Absorption in COVID Patients

September 01, 2021 (Lausanne, Switzerland). Ormendes SA is proud to announce the results of a clinical study conducted with its probiotic product (Sivomixx®800). This probiotic formulation induces an “oxygen-sparing effect” and modulates the consumption of oxygen in the gut making it available for other critical organs, i.e,. brain, heart and liver. Sivomixx®800 has been evaluated in a controlled trial with sixty-nine adult COVID-19 patients with a confirmed diagnosis of SARS-CoV-2 related pneumonia (1). All patients in the study required non-invasive oxygen therapy. Patients supplemented with the probiotic, in addition to the standard therapy, showed significantly higher blood oxygen levels than those on routine therapy alone while patients on standard treatment had significantly higher oxygen requirements. In addition, fewer patients in the probiotic group were transferred to the intensive care unit (2.5% in the probiotic group vs 13.8% in the control group).

This study confirms previous clinical studies (2, 3) and extends the knowledge on the mechanisms by which COVID-19-infected patients have a higher chance of survival and a reduced risk of respiratory failure when supplemented with SLAB51.

The unique property of the SLAB51 probiotic formula opens a new promising scenario for the prevention and treatment of numerous health conditions where the need for oxygen is not fully satisfied. In this context, could represent a safe add-on to the standard of care drugs for a wide spectrum of invalidating diseases such as chronic fatigue, neurodegenerative disorders, neonatal hypoxia and myocardial ischemia.

Sivomixx®800 is available for international license. For information, contact

Sivomixx®800 by Ormendes SA.

Ormendes is a biotechnology company focused on the development and commercialization of live biotherapeutic medicines ( Sivomixx® 800 is a probiotic food supplement, finalist of the Nutraingredients Awards Best Probiotic 2021 ( These are independent studies conducted by clinicians and researchers in the front line helping Covid-19 patients.


  1. Ceccarelli G. et al. Oxygen Sparing Effect of Bacteriotherapy in COVID-19 Nutrients 2021, 13(8), 2898;
  2. d’Ettorre G, Ceccarelli G, Marazzato M, Campagna G, Pinacchio C, Alessandri F, et al. Challenges in the Management of SARS-CoV2 Infection: The Role of Oral Bacteriotherapy as Complementary Therapeutic Strategy to Avoid the Progression of COVID-19. Front Med (Lausanne). 2020;7:389. 10.3389/fmed.2020.00389
  3. Ceccarelli G, Borrazzo C, Pinacchio C, Santinelli L, Innocenti GP, Cavallari EN, et al. Oral Bacteriotherapy in Patients With COVID-19: A Retrospective Cohort Study. Front Nutr. 2020;7:613928. 10.3389/fnut.2020.613928

For more information, contact Ormendes at Sivomixx® is a Trademark of Ormendes SA

Tags: oxygenation, bacteriotherapy, Ormendes SA probiotics, Sivomixx, Probiotic Product, Slab51, COVID-19