Overview
Migraine symptoms are more than a typical allergy- or stress-related headache. Migraine attacks can last from 4 to 72 hours. Your symptoms can be aggravated by even the most simple activities like moving around or being in close proximity to light and noise.
Although pain medication can temporarily relieve symptoms of migraine attacks you might be concerned about side effects. CBD could be your solution.
The cannabis plant contains CBD, one of many active compounds. CBD is a natural treatment for certain medical conditions.
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Continue reading to learn more:
- What the latest research has to say about CBD and migraine
- How it works
- Side effects possible and more
What the research has to say about CBD
There is very little research on CBD and migraine. Existing studies examine the combined effects CBD and Tetrahydrocannabinol (THC), a different cannabinoid. No studies have been published that study the effects of CBD on migraine.
The limitations of research on CBD and the obstacles to legalization are partly responsible for this. Some laboratory studies suggest that CBD oil might help with all forms of chronic pain and acute pain, including migraine.
Study of CBD and THC
2017 was the 3rd Congress of the European Academy of Neurology. A group of researchers presented the results of their research on migraine prevention and cannabinoids.
Phase I of the study involved 48 patients suffering from chronic migraine who were treated with a combination of two compounds. The first compound contained 19% THC and the second contained 9 percent CBD. There was virtually no THC in either compound. These compounds were taken orally.
Doses under 100 milligrams (mg) had no effect. Acute pain decreased by 55 percent when the dose was increased to 200mg. The study’s second phase focused on people suffering from chronic migraine or cluster headaches. The daily dosage for chronic migraine was 200 mg of THC-CBD from phase I and 25 mg of amtriptyline. This tricyclic antidepressant was given to the 79 participants.
Cluster headache sufferers received 200mg of THC-CBD from phase I daily or 480mg of verapamil as a calcium channel blocking.
The treatment lasted three months and was followed up by a four-week follow-up.
Combination THC-CBD reduced migraine attacks by 40 percent. Amitriptyline was responsible for a reduction of migraine attacks by just 40.1 percent. THC-CBD combined also decreased the intensity of pain by 43.5 percent.
Cluster headache sufferers saw only a slight reduction in their headache frequency and severity.
Some participants did however notice a drop in their pain intensity of 43.5 percent. Participants who had suffered from migraine attacks since childhood were not affected by this drop in intensity.
Researchers concluded that acute cluster headaches could only be treated with cannabinoids if the sufferer had suffered from migraine attacks as a child.
Other cannabis research
For those suffering from migraine pain, research on other cannabis forms may offer additional relief.
Studies about medical marijuana
Pharmacotherapy published a study in 2016 on the use and effects of medical cannabis for migraine. Research showed that 39% of those surveyed reported less migraine attacks.
The most common complaint was drowsiness. Others had trouble figuring out how much to take. Side effects were more common in those who ingested edible marijuana than those who inhaled it or used other forms. The 2018 study examined 2,032 individuals with migraine, headache or arthritis or chronic pain as their primary symptom. The majority of participants were able replace their prescription medication, which was opioids and opiates, with cannabis.
All subgroups preferred cannabis. People with migraines and headaches preferred OG Shark, a mix of high-THC and low CBD.
Study of nabilone
A 2012 Italian study examined the effects of nabilone (a synthetic version of THC) on headache disorders. 26 people with medication-overuse headaches took either.50 mg per day of Nabilone or 400mg per day of Ibuprofen.
The study participants were given one drug for eight weeks and then went without it for one week. They switched to the second drug for the remaining eight weeks.
Both drugs were effective. Participants reported greater improvements in their quality of life and improved quality of living after taking nabilone.
Nabilone caused less severe pain and a lower drug dependence. Researchers found that neither drug had any significant effect on migraine frequency. This was due to the brief duration of the study.
How CBD works
CBD interacts with the body’s cannabinoid receptors (CB1 & CB2) . Although the mechanisms of CBD interaction are not fully understood, they can impact the immune system.
CBD could hinder the body’s ability to metabolize anandamide. Anandamide is associated with pain regulation. High levels of anandamide may help reduce pain feelings. It is also believed that CBD can limit inflammation in the body. This may help to reduce pain and other immune system responses.
To understand the effects of CBD on the body, more research is required.
How to Use CBD
Although the United States is currently weighing the merits and uses of cannabis and related products in Congress, its medicinal benefits are not new.
The National Center for Complementary and Integrative Health. states that cannabis has been used as an alternative medicine for more than 3,000 years. These uses include:
- Pain
- Neurological symptoms
- inflammation
CBD oil can be used in:
- ingested
- Topically applied
Oral CBD is less likely than vaping to cause side effects, so beginners might want to start there. You can:
- Place a few drops under your tongue to get some oil.
- CBD capsules
- CBD-infused treats can be eaten or drank
If you suffer from severe migraines at home, vaping CBD oil could be a good option. You don’t need to go anywhere.
The National Cancer Institute explains how inhalation delivers the compounds to your bloodstream faster than other methods.
There are currently no guidelines regarding proper dosage in migraine attacks. Discuss your doctor’s recommendations to determine the right dosage.
Start with the lowest possible dosage if you are new to CBD oil. Gradually increase the recommended dosage. This will help your body get used to the oil, and decrease your chance of side effects.
Possible side effects and potential risks
Studies have shown that CBD and CBD oil have minimal side effects. This is why many people are avoiding prescription pain medication and over-the-counter (OTC).
However, it is possible to feel tired, drowsy, or upset stomach. There may also be changes in appetite or weight. Liver toxicities have also been reported in mice that were force-fed high doses of CBD-rich marijuana extract.
The way that CBD oil is used can affect the risk of side effects. For example, vaping may cause lung irritation. This could lead to:
- Chronic cough
- wheezing
- breathing difficulties
Your doctor might recommend against vaping CBD oil if you have asthma and other types of lung disease.
Talk to your doctor if you are unsure about side effects and how your body may handle them.
Drug interactions are important to consider if you take other medications or dietary supplements. CBD can interact with many drugs including:
- Antibiotics
- antidepressants
- Blood thinners
You should be extra cautious if you are taking a supplement or medication that interacts with grapefruit. Both CBD and grapefruit interact with enzymes, such as cytochromes 450 (CYPs), which are essential for drug metabolism.
Will CBD get you high?
CBD oils can be made from cannabis but don’t always contain THC. THC, the cannabinoid responsible for making users feel high or stoned when they smoke cannabis, is what CBD oils are made from.
There are two types of CBD strains available:
- Dominant
- rich
The CBD-rich strain has both THC and CBD.
CBD that doesn’t contain THC isn’t psychoactive. According to the Project CBD, CBD can often counteract the effects of THC even if you choose a combination product. This is just one reason CBD oil might be preferred to medical marijuana.
Is CBD legal? Marijuana-derived CBD products may be illegal at the federal level but they are permitted under certain state laws. Hemp-derived CBD products (with less THC than 0.3%) are legal at the federal level but are still illegal according to some state laws. You should check the laws in your state and any country you are visiting. Nonprescription CBD products may not be FDA-approved and could be incorrectly labeled.
Legality
Some areas of the United States still ban cannabis due to its psychoactive properties.
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A growing number of states, however, have voted to legalize cannabis for medical purposes only. Others legalize cannabis for recreational and medicinal use. You should also have CBD oil if you reside in a state that legalizes marijuana for recreational and medicinal use.
If your state has legalized marijuana for medicinal purposes, you will need to apply for a cannabis card through your doctor before buying CBD products. You will need this license to consume all forms of cannabis including CBD.
All forms of cannabis in some states are illegal. Federally, cannabis remains a dangerous and illegal drug. It is important to know the laws of your state as well as any other states that you might visit. You could be penalized for possessing cannabis-related products that are illegal or require a medical licence you don’t possess.
Talk with your doctor
CBD oil is still being researched and may not be a standard treatment for migraines. However, it is worth speaking to your doctor if you are interested. Your doctor can help you determine the right dosage and any legal requirements.
CBD oil should be treated as any other treatment for migraine. It may take some time for it to start working and you might need to adjust the dosage to suit your needs.
Original Source of the original story >> CBD Oil for Migraine – Does It Work?
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